Preprints:

Benegal AN, He Y, Ho K, Groff G, Guo Z, Vahey MD. Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities. [preprint] bioRxiv November 22, 2024; DOI: 10.1101/2024.11.20.624560

He Y, Guo Z, Vahey MD. Modulation of B cell receptor activation by antibody competition. [preprint] bioRxiv November 21, 2024; DOI: 10.1101/2024.11.18.624200.

Publications:

Mitrovich, MD; Vahey, MD. Genetically Recoding Respiratory Syncytial Virus to Visualize Nucleoprotein Dynamics and Virion Assembly. ACS Infect. Dis. 2025, 11 (1), 95–103. DOI: 10.1021/acsinfecdis.4c00321.

Wang S.J., Gupta R., Benegal A., Avula R., Huang Y-Y, Vahey M.D., Chakrabarty R.K., Pappu R.V., Singamaneni S., Puthussery J.V., King M.R. A High-Avidity, Thermostable, and Low-Cost Synthetic Capture for Ultrasensitive Detection and Quantification of Viral Antigens and Aerosols. ACS Sens. May 16, 2024. doi: 10.1021/acssensors.4c00282

King M.R., Ruff K.M., Lin A.Z., Pant A., Farag M., Lalmansingh J.M., Wu T., Fossat M.J., Ouyang W., Lew M.D., Lundberg E., Vahey M.D., Pappu R.V. Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient. Cell. 2024 April 11; 187(8) 1889-1906.e24. doi: 10.1016/j.cell.2024.02.029.

He, Y., Guo, Z., Subiaur, S., Benegal, A.N., Vahey, M.D. Antibody inhibition of influenza A virus assembly and release. J Virol, Vol. 98, No. 2 (2024). DOI: 10.1128/jvi.01398-23 (code)

Guo, Z., He, Y., Xu, J., Benegal, A.N., Brody, S.L., Vahey, M.D. Neuraminidase activity modulates cellular co-infection during influenza A virus multicycle growth. mBio, Vol. 14, No. 3 (2023). DOI: 10.1128/mbio.03591-22 (code)

Zhang O., Guo Z., He Y., Wu T., Vahey M.D., Lew M.D. Six-Dimensional Single-Molecule Imaging with Isotropic Resolution using a Multi-View Reflector Microscope. Nat Photonics. 2023 Feb;17(2):179-186. doi: 10.1038/s41566-022-01116-6. Epub 2022 Dec 5. PubMed PMID: 36968242; PubMed Central PMCID: PMC10035538.

Kuppan, J. P., Mitrovich, M. D. & Vahey, M. D. A morphological transformation in respiratory syncytial virus leads to enhanced complement deposition. eLife 10, e70575 (2021). DOI: 10.7554/eLife.70575

Zang R, Case JB, Yutuc E, Ma X, Shen S, Gomez Castro MF, Liu Z, Zeng Q, Zhao H, Son J, Rothlauf PW, Kreutzberger AJB, Hou G, Zhang H, Bose S, Wang X, Vahey MD, Mani K, Griffiths WJ, Kirchhausen T, Fremont DH, Guo H, Diwan A, Wang Y, Diamond MS, Whelan SPJ, Ding S. Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. Proc Natl Acad Sci U S A2020 Dec 15;117(50):32105-32113doi: 10.1073/pnas.2012197117Epub 2020 Nov 25. PubMed PMID: 33239446; PubMed Central PMCID: PMC7749331.

Armstrong M, Vahey MD, Hunt TP, Fletcher DA. Forming and loading giant unilamellar vesicles with acoustic jetting. Biomicrofluidics2020 Nov;14(6):064105doi: 10.1063/5.0021742eCollection 2020 Nov. PubMed PMID: 33269034; PubMed Central PMCID: PMC7679179.

Vahey, M.D., D.A. Fletcher, “Influenza A virus surface proteins are organized to help penetrate host mucus,” eLife 2019;8:e43764 DOI: 10.7554/eLife.43764

Vahey, M.D., D.A. Fletcher, “Low fidelity assembly of influenza A virus promotes escape from host cells,” Cell. DOI: 10.1016/j.cell.2018.10.056

Lu, P., D. Min, F. DiMaio K.Y. Wei, M.D. Vahey, S.E. Boyken, Z. Chen, J.A. Fallas, G. Ueda, W. Sheffler, V.K. Mulligan, W. Xu, J.U. Bowie, D. Baker, “Accurate computational design of multipass transmembrane proteins,” Science 359(6379): pp.1042-1046 (2018). DOI: 10.1126/science.aaq1739

Vahey, M.D., D.A. Fletcher, “The biology of boundary conditions: cellular reconstitution in one, two, and three dimensions,” Current Opinion in Cell Biology 26: pp. 60-68 (2014). DOI: 10.1016/j.ceb.2013.10.001

Good, M.C., M.D. Vahey, A. Skandarajah, D.A. Fletcher, R. Heald, “Cytoplasmic volume modulates spindle size during embryogenesis,” Science 342(6160): pp. 856-860 (2013). DOI: 10.1126/science.1243147

Vahey, M.D., J.P. Svensson, L. Quiros-Pesudo, L.D. Samson, and J. Voldman, “Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae,” Lab on a Chip 13: pp. 2754-63 (2013). DOI: 10.1039/C3LC50162K

Vahey, M.D. and J. Voldman, “Emergent behavior in particle-laden microfluidic systems informs strategies for improving cell and particle separations,” Lab on a Chip 11: p 2071-80 (2011). DOI: 10.1039/C0LC00602E

Vahey, M.D. and J. Voldman, “High-throughput cell and particle characterization using iso-dielectric separation,” Analytical Chemistry 81(7): pp. 2446-55 (2009).  DOI: 10.1021/ac8019575

Desai, S.P., M.D. Vahey, and J. Voldman, “Electrically addressable vesicles – tools for dielectrophoresis metrology,” Langmuir 25(6): pp. 3867-75 (2009). DOI: 10.1021/la803330c

Vahey, M.D. and J. Voldman, “An equilibrium method for continuous-flow cell sorting using dielectrophoresis,” Analytical Chemistry 80(9): pp. 3135-43 (2008). DOI: 10.1021/ac7020568

Barsotti, R.J., M.D. Vahey, R. Wartena, Y.-M. Chiang, J. Voldman and F. Stellacci. “Assembly of metal nanoparticles into nanogaps.” Small 3(3): pp. 488-99 (2007). DOI: 10.1002/smll.200600334

Kim, L.Y., M.D. Vahey, H.-Y. Lee, and J. Voldman, “Microfluidic arrays for logarithmically perfused embryonic stem cell culture,” Lab on a Chip 6: pp. 394-406 (2006). DOI: 10.1039/B511718F